The Mouse: Keep in mind that much of the earlier animal research and resulting anti-cannabis propaganda was based on HUGE i.v. doses of THC.

Important facts are often not considered by those digesting results for public consumption. Political arguments are often based on misunderstood or twisted truth. In this case, the mouse might be assumed by the uninformed as a 'typical result', ignoring that 1) Some of the different metabolic byproducts also contribute to the effect 2) Often an absurdly high dose was used (mg/kg) 3) Different animals respond uniquely and have different receptor densities. 4) Each method of 'taking' a drug gives vastly different results (e.g. Eating a brownie produces a different effect than inhalation of an equivalent amount of active ingredients.)

Pharmacology, Pharmaco-kinetics & Pharmaco-dynamics

Robert Melamede, Ph.D. - Cancer & Cannabinoids

University of Colorado Research